RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs
نویسندگان
چکیده
منابع مشابه
RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs
BACKGROUND There is a need for more powerful methods to identify low-effect SNPs that contribute to hereditary COPD pathogenesis. We hypothesized that SNPs contributing to COPD risk through cis-regulatory effects are enriched in genes comprised by bronchial epithelial cell (BEC) expression patterns associated with COPD. METHODS To test this hypothesis, normal BEC specimens were obtained by br...
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ژورنال
عنوان ژورنال: BMC Pulmonary Medicine
سال: 2018
ISSN: 1471-2466
DOI: 10.1186/s12890-018-0603-y